J Dentofacial Anom Orthod
Volume 18, Number 3, 2015OSAHS of the child
|Number of page(s)||13|
|Published online||17 April 2018|
Genetics of sleep disordered breathing (syndromes excluded)
INSERM, UMR1153, Center of research in epidemiology and statistics, Sorbonne University Paris – Cité (CRESS), Early origins of child health and development team (ORCHAD), 94807
Paris-Descartes University, France
Address for correspondence: Sabine Plancoulaine INSERM U1153 Eq6 16 Avenue Paul Vaillant-Couturier 94807 Villejuif Cedex – France email@example.com
Accepted: 25 February 2015
The objective of this article is to present the approach, the main methods and the main results obtained in the study of the genetics of sleep disordered breathing. It is not an exhaustive systematic review of the literature but a didactic presentation to aid understanding of current research in the domain. It highlights the existence of a genetic predisposition to developing respiratory sleep disorder, from simple snoring to sleep apnea syndrome. The genes and pathways most frequently identified are those involved in inflammation.
Key words: Sleep disordered breathing / OSAHS / genetic predisposition / risk factors / inflammation
© The authors
This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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